Study: Ozempic Users Significantly Reduce Physical Activity After Starting GLP-1s

Executive Briefing

• Reveals GLP-1 users averaged 560 fewer daily steps and 6 fewer minutes of exercise after starting medication
• Warns that reduced activity risks muscle loss, as GLP-1 drugs decrease both fat and lean muscle mass
• Finds calorie deficit and side effects like nausea and fatigue may suppress motivation to exercise
• Stresses resistance training and daily movement are essential, not optional, for GLP-1 patients
• Notes expert disagreement, with some clinicians reporting patients become more active under close supervision